BDBM50464748 CHEMBL4284595

SMILES Nc1cc(-c2ccco2)c2oc(nc2c1)-c1ccco1

InChI Key InChIKey=CFHKTWHFWORIBL-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50464748   

TargetAdenosine receptor A1(Homo sapiens (Human))
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50464748(CHEMBL4284595)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50464748(CHEMBL4284595)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes after 1 hr by TopCount microplate scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50464748(CHEMBL4284595)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptor incubated for 60 mins and measured by by scintillation counting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50464748(CHEMBL4284595)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cells and measured by [35S]-GTPS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Umr-S1172 - Jparc - Centre De Recherche Jean-Pierre Aubert Neurosciences Et Cancer

Curated by ChEMBL
LigandPNGBDBM50464748(CHEMBL4284595)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cell membranes assessed as inhibition of CGS241680-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed