BDBM50465297 CHEMBL4283230

SMILES COc1cc2NC(=O)C(C)(C)Oc2cc1NS(=O)(=O)c1cc(Br)ccc1OC

InChI Key InChIKey=BVPMJOFBUGYDAV-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465297   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50465297(CHEMBL4283230)
Affinity DataKd:  302nMAssay Description:Binding affinity to human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells by isothermal titration calorime...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50465297(CHEMBL4283230)
Affinity DataIC50:  690nMAssay Description:Inhibition of human His6-tagged BRD4 BD1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells using H-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB