BDBM50467593 CHEMBL4284259

SMILES Cc1csc(NC(=O)c2ccc(CNc3ccccc3C)cc2)n1

InChI Key InChIKey=DHPPBCAZAYICNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467593   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50467593(CHEMBL4284259)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant human SCD1 expressed in baculovirus expression system assessed as reduction in [3H]H2O production using stearoyl [9,10-3H]C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50467593(CHEMBL4284259)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of mouse liver microsome SCD assessed as reduction in [3H]H2O production using stearoyl [9,10-3H]CoA as substrate in presence of NADH incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50467593(CHEMBL4284259)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of delta-5 fatty acid desaturase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed