BDBM50494806 CHEMBL3094349

SMILES CCNC(=O)Nc1nc2cc(cc(-c3ccccn3)c2s1)-c1cnc(nc1)N1CCC(CC1)C(O)=O

InChI Key InChIKey=RPPRAYQNSDDYNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50494806   

TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandPNGBDBM50494806(CHEMBL3094349)
Affinity DataIC50:  23.8nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50494806(CHEMBL3094349)
Affinity DataIC50: <198nMAssay Description:Inhibition of Escherichia coli DNA gyrase B incubated for 60 mins by malachite green dye based spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandPNGBDBM50494806(CHEMBL3094349)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed