BDBM50500929 CHEMBL3800231

SMILES COCCN(Cc1cc(cc2c1oc(cc2=O)N1CCO[C@H](C)C1)C(=O)N(C)C)c1cc(F)cc(F)c1

InChI Key InChIKey=ODXMHNGQPZYRBV-QGZVFWFLSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500929   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50500929(CHEMBL3800231)Copy SMILESCopy InChI

Affinity DataIC50:  5nMAssay Description:Inhibition of PI3Kbeta in PTEN deficient human MDA-MB-468 cells assessed as inhibition of AKT phosphorylation at Ser-473 residue after 2 hrs by plate...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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