BDBM50502489 CHEMBL4583704::US11834430, Compound 72
SMILES COc1cc(ccc1O[C@@H](C)COc1cccc(c1)-n1ccnc1C)C#N
InChI Key InChIKey=SILCBNWSDQDKBJ-HNNXBMFYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50502489
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Usona Institute
Curated by ChEMBL
Usona Institute
Curated by ChEMBL
Affinity DataIC50: 0.680nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair