BDBM50503685 CHEMBL4092241

SMILES [H][C@]12CN3CC(=C1)[C@]1([H])CCN(C[C@@]1([H])CC\C=C/CCCC3)CCCC\C=C/CC2

InChI Key InChIKey=UOAQLFVPXKOHCQ-ZUCXHZAFSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50503685   

TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta2 trypsin-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50:  440nMAssay Description:Inhibition of 20s immunoproteasome LMP2 in human erythrocytes using Ac-Pro-Ala-Leu-MCA as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of 20s immunoproteasome MECL1 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50:  420nMAssay Description:Inhibition of 20s constitutive proteasome beta5 chymotrypsin-like activity in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50:  480nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50503685(CHEMBL4092241)
Affinity DataIC50:  630nMAssay Description:Inhibition of 20s immunoproteasome LMP7 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed