BDBM50505975 CHEMBL4473049

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1cc2ccc3cc(ccc3c2s1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key InChIKey=LBKDKNHRWUOYBN-PANORKHLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50505975   

TargetNonstructural protein 5A(Hepatitis C virus)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505975(CHEMBL4473049)
Affinity DataIC50:  0.0120nMAssay Description:Inhibition of NS5A in HCV genotype 1b infected in human HuH7.5/Con1/SG-Neo(I)-hRluc2aUb cells assessed as inhibition of replicon levels incubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505975(CHEMBL4473049)
Affinity DataIC50:  0.00500nMAssay Description:Inhibition of NS5A in HCV genotype 2a infected in human Huh7.5/J6/JFH1/EMCVIRES/hRlucNeo cells assessed as inhibition of replicon levels incubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505975(CHEMBL4473049)
Affinity DataIC50:  0.0280nMAssay Description:Inhibition of NS5A in HCV genotype 6a infected in human HuH7.5/Con1/SG-Neo(I)-hRluc2aUb cells assessed as inhibition of replicon levels incubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505975(CHEMBL4473049)
Affinity DataIC50:  0.0470nMAssay Description:Inhibition of NS5A in HCV genotype 3a infected in human HuH7.5/Con1/SG-Neo(I)-hRluc2aUb cells assessed as inhibition of replicon levels incubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505975(CHEMBL4473049)
Affinity DataIC50:  0.00300nMAssay Description:Inhibition of NS5A in HCV genotype 4a infected in human HuH7.5/Con1/SG-Neo(I)-hRluc2aUb cells assessed as inhibition of replicon levels incubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Lupin

Curated by ChEMBL
LigandPNGBDBM50505975(CHEMBL4473049)
Affinity DataIC50:  0.0270nMAssay Description:Inhibition of NS5A in HCV genotype 1a infected in human HuH7.5/Con1/SG-Neo(I)-hRluc2aUb cells assessed as inhibition of replicon levels incubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed