BDBM50508413 CHEMBL4459166
SMILES [2H]C([2H])([2H])C1(CC1)NS(=O)(=O)c1ccc2n(Cc3ccn(C)n3)c(=O)n(Cc3cnn(C)c3)c(=O)c2c1
InChI Key InChIKey=YIIIUBIPEMDTEA-FIBGUPNXSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50508413
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair