BDBM50508535 CHEMBL4465124

SMILES CC(=O)N1CCCC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1

InChI Key InChIKey=LMTJCDVVVWIRJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508535   

Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita

Curated by ChEMBL
LigandPNGBDBM50508535(CHEMBL4465124)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita

Curated by ChEMBL
LigandPNGBDBM50508535(CHEMBL4465124)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of PFKFB3 in human HCT116 cell lysates assessed as reduction in glycolytic-flux induced fructose-2,6-bisphosphate formation using fructose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed