BDBM50508553 CHEMBL4467929
SMILES CC(=O)N1CCOC(CNC(=O)c2ccncc2Nc2cc(-c3ccc4ccn(C)c4c3)c3nccnc3c2)C1
InChI Key InChIKey=IMQDTQGFCHAOHO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50508553
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita
Curated by ChEMBL
Selvita
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PFKFB3 in human HCT116 cell lysates assessed as reduction in glycolytic-flux induced fructose-2,6-bisphosphate formation using fructose...More data for this Ligand-Target Pair
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita
Curated by ChEMBL
Selvita
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G...More data for this Ligand-Target Pair