BDBM50508554 CHEMBL4459213

SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2cnccc2C(=O)NCC2COCCN2)cc2nccnc12

InChI Key InChIKey=HSRKTKSTDXBXJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508554   

Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita

Curated by ChEMBL
LigandPNGBDBM50508554(CHEMBL4459213)
Affinity DataIC50:  4.17E+4nMAssay Description:Inhibition of PFKFB3 in human HCT116 cell lysates assessed as reduction in glycolytic-flux induced fructose-2,6-bisphosphate formation using fructose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita

Curated by ChEMBL
LigandPNGBDBM50508554(CHEMBL4459213)
Affinity DataIC50:  33nMAssay Description:Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed