BDBM50510048 CHEMBL4442568
SMILES Cc1nn(c(C)c1-c1ccc(F)cc1)-c1ncnc2CNCc12
InChI Key InChIKey=VVJISDCXPCMGDZ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50510048
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of pH 5.5-stimulated mouse ASIC2a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP1A2 (unknown origin) using pro-luciferin substrates in presence of NADPH by firefly luciferase reporter gene based P450-Glo assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Promidis
Curated by ChEMBL
Promidis
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG incubated for 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair