BDBM50515598 CHEMBL4526049

SMILES COc1cc(N)c(Cl)cc1C(=O)CCC1CCN(Cc2ccc(O)c(O)c2)CC1

InChI Key InChIKey=WJKHUZSNGGHVOF-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50515598   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataKi:  5.90nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataIC50:  138nMAssay Description:Inhibition of human erythrocytes AChE assessed as reduction in 5-thio-2-nitrobenzoate anion formation using acetylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataEC50:  2.80nMAssay Description:Partial agonist activity at human HA-tagged 5HT4 receptor expressed in COS7 cells assessed as induction of cAMP production measured after 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50515598(CHEMBL4526049)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed