BDBM50517299 CHEMBL4533718
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC(C3CCC3)C3CCC3)ncnc12
InChI Key InChIKey=VQFKOPZALUTGKJ-BGIGGGFGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50517299
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 897nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from mouse A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical College Of Wisconsin
Curated by ChEMBL
Medical College Of Wisconsin
Curated by ChEMBL
Affinity DataKi: 1.78E+3nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.55E+3nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5-N-ethylcarboxamidoadenosine from human A2A adenosine receptor expressed in HEK293 cell m...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical College Of Wisconsin
Curated by ChEMBL
Medical College Of Wisconsin
Curated by ChEMBL
Affinity DataKi: 4.82E+3nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from human A3A adenosine receptor expressed in CHO cell membranes after ...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in HEK cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP production after 60 minsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Medical College Of Wisconsin
Curated by ChEMBL
Medical College Of Wisconsin
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 209nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in CHOKI cells assessed as induction of beta-arrestin2 recruitment after 60 minsMore data for this Ligand-Target Pair