BDBM50524298 CHEMBL4577258

SMILES CC(O)=O.CNc1nc(Nc2cnc(C#N)c(O[C@@H]3CCCNC3)c2)ncc1-c1cnn(C)c1

InChI Key InChIKey=GZTCTVFBVJLJOM-XFULWGLBSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50524298   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of LCK (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human C-terminal His-tagged FLT3 (M1 to N541 residues) expressed in HEK293 cells using biotin-labelled STK substrate-1 as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCepsilon (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  626nMAssay Description:Inhibition of p70S6K (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  736nMAssay Description:Inhibition of PIM3 (unknown origin) incubated for 60 mins using biotin-labelled STK substrate-1 as substrate by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  108nMAssay Description:Inhibition of AMPKalpha1beta1gamma1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  512nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged PIM1 (1 to 313 residues) expressed in baculovirus expression system using biotin-la...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CHK2 (M1 to L543 residues) expressed in baculovirus infected insect cells using biotin-labelled...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of LYN (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of BLK (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50524298(CHEMBL4577258)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CHK1 (M1 to T476 residues) expressed in baculovirus infected insect cells using biotin-labelled...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed