BDBM50526042 CHEMBL4579238

SMILES CCOc1ccc(Oc2ccc(cc2)-c2cnc(o2)-c2cc(O)c(O)c(Br)c2Br)cc1

InChI Key InChIKey=MOHJRHPKFDUKBW-UHFFFAOYSA-N

Data  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50526042   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataIC50:  190nMAssay Description:Inhibition of GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli using pNPP as substrate measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataIC50: >3.68E+4nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataIC50: >3.68E+4nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of TCPTP (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataKd:  2.23E+3nMAssay Description:Binding affinity to human PTP1B (1 to 321 residues) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataIC50: >3.68E+4nMAssay Description:Inhibition of LAR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50526042(CHEMBL4579238)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of PTP1B A27S mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed