BDBM50527303 CHEMBL4464572::US10829446, Compound 95

SMILES Cc1cc(OCC=C)cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F

InChI Key InChIKey=FEYQZXJYMGGAIM-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527303   

TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University

US Patent
LigandPNGBDBM50527303(CHEMBL4464572 | US10829446, Compound 95)
Affinity DataIC50:  50nMAssay Description:Active Moz protein was expressed as N-terminal fusion protein with a His6 tag in BL21 E. coli cells. Protein purification was performed via nickel-im...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Monash University

US Patent
LigandPNGBDBM50527303(CHEMBL4464572 | US10829446, Compound 95)
Affinity DataIC50:  54nMAssay Description:Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed