BDBM50534268 CHEMBL4571632

SMILES COc1c(N2CCN(CNc3ccc(cc3)S(=O)(=O)Nc3nc(C)cc(C)n3)C(C)C2)c(F)cc2c1n(cc(C(O)=O)c2=O)C1CC1

InChI Key InChIKey=KXCIONFMKNNVNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534268   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50534268(CHEMBL4571632)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 15 mins by PAGE analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed