BDBM50534325 CHEMBL4534918

SMILES CC1CN(CC(C)O1)c1ccc(cc1)C1(CC(O)=C(Sc2ccccc2Cl)C(=O)N1)c1ccsc1

InChI Key InChIKey=ZIDMXFRRFITNKV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50534325   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534325(CHEMBL4534918)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534325(CHEMBL4534918)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of LDHA in human MiPaca2 cells assessed as inhibition of lactate productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534325(CHEMBL4534918)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed