BDBM50542023 CHEMBL4649653
SMILES COc1ccc(C(=O)N2[C@H](C)CN(C[C@H]2C)C(=O)c2ccc3cc[nH]c3c2)c(F)c1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50542023
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine
Curated by ChEMBL
H3 Biomedicine
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of CPS1 in human pooled hepatocytes assessed as reduction in urea production measured after 16 hrs in presence of NH4Cl by tecan-plate rea...More data for this Ligand-Target Pair
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine
Curated by ChEMBL
H3 Biomedicine
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair