BDBM50542023 CHEMBL4649653

SMILES COc1ccc(C(=O)N2[C@H](C)CN(C[C@H]2C)C(=O)c2ccc3cc[nH]c3c2)c(F)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542023   

TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine

Curated by ChEMBL
LigandPNGBDBM50542023(CHEMBL4649653)
Affinity DataIC50:  240nMAssay Description:Inhibition of CPS1 in human pooled hepatocytes assessed as reduction in urea production measured after 16 hrs in presence of NH4Cl by tecan-plate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine

Curated by ChEMBL
LigandPNGBDBM50542023(CHEMBL4649653)
Affinity DataIC50:  66nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed