BDBM50553401 CHEMBL4778265
SMILES C[C@H](O)COc1nc(nc(N)c1C(=O)NCc1ncccc1C)-c1ccco1
InChI Key InChIKey=CZOGJFVDQVTTBG-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50553401
Affinity DataKi: 0.110nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A1 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine A3 receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Antagonist activity at adenosine 2A receptor in human PBMC assessed as reversal of NECA/CD3/CD28-stimulated IL-2 release incubated for 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: >200nMAssay Description:Antagonist activity at adenosine 2A receptor in human blood assessed as reversal of NECA/LPS-stimulated TNF-alpha release incubated for 5 hrsMore data for this Ligand-Target Pair