BDBM50553403 CHEMBL4747929
SMILES COc1nc(nc(N)c1C(=O)NCc1c(Cl)cccc1Cl)-c1ncco1
InChI Key InChIKey=MZALOVKMJUTVDD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50553403
Affinity DataKi: 0.0780nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2B receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at adenosine 2A receptor in human whole blood assessed as reduction in phosphorylated CREB level preincubated for 20 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: >200nMAssay Description:Antagonist activity at adenosine 2A receptor in human blood assessed as reversal of NECA/LPS-stimulated TNF-alpha release incubated for 5 hrsMore data for this Ligand-Target Pair