BDBM50640 2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,4-dione::2-chloro-3-(1H-indazol-6-ylamino)-1,4-naphthoquinone::2-chloro-3-(1H-indazol-6-ylamino)naphthalene-1,4-dione::MLS000737237::SMR000528477::cid_265940

SMILES ClC1=C(Nc2ccc3cn[nH]c3c2)C(=O)c2ccccc2C1=O

InChI Key InChIKey=NYOUWELKHWCYQM-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50640   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataIC50:  6.25E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
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TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataEC50:  6.22E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
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TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataEC50:  5.42E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMitochondrial peptide methionine sulfoxide reductase(Bos taurus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataIC50: >1.55E+5nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetC-C chemokine receptor type 6(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataIC50: >6.66E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMultidrug resistance protein CDR2(Candida albicans)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataEC50:  4.06E+4nMAssay Description:UNMCMD Assay Overview: Assay Support: 1 R03 MH087406-01A1 Project Title: Identification of broad-spectrum antifungal efflux pump inhibitors ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMitochondrial peptide methionine sulfoxide reductase(Bos taurus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataEC50: >1.04E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-galactosidase(Escherichia coli)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50640(2-chloranyl-3-(1H-indazol-6-ylamino)naphthalene-1,...)
Affinity DataIC50: >6.66E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay