BDBM51932 5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide::5-(4-chlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide::5-(4-chlorophenyl)-N-[4-(4-methylpiperazino)phenyl]-2-furamide::CHEMBL1392696::MLS001125449::SMR000665983::cid_1494312

SMILES CN1CCN(CC1)c1ccc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1

InChI Key InChIKey=QONRQALSXOAURD-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 51932   

LigandPNGBDBM51932(5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)ph...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM51932(5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)ph...)
Affinity DataEC50:  2.26E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM51932(5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)ph...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of MK2 using Acam peptide as substrate incubated for 30 mins prior to substrate addition measured after 10 mins using 100 uM ATP by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM51932(5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)ph...)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation in IL-1beta stimulated human SW1353 cells incubated for 30 mins prior to IL-1beta-stimulation measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein LANA1(Human herpesvirus 8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM51932(5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)ph...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay