BDBM53556 1-(1,3-benzodioxol-5-yl)-3-(1-benzyl-4-piperidyl)urea::1-(1,3-benzodioxol-5-yl)-3-(1-benzylpiperidin-4-yl)urea::1-(1,3-benzodioxol-5-yl)-3-[1-(phenylmethyl)-4-piperidinyl]urea::1-(1,3-benzodioxol-5-yl)-3-[1-(phenylmethyl)piperidin-4-yl]urea::MLS000050082::N-1,3-benzodioxol-5-yl-N'-(1-benzyl-4-piperidinyl)urea::SMR000077111::US11116757, No. B22::cid_2211100

SMILES O=C(NC1CCN(Cc2ccccc2)CC1)Nc1ccc2OCOc2c1

InChI Key InChIKey=ZVMREXLJGLBENK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 53556   

TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53556(1-(1,3-benzodioxol-5-yl)-3-(1-benzyl-4-piperidyl)u...)
Affinity DataIC50:  1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Homo sapiens)
Memorial Sloan Kettering Cancer Center

US Patent
LigandPNGBDBM53556(1-(1,3-benzodioxol-5-yl)-3-(1-benzyl-4-piperidyl)u...)
Affinity DataIC50: >1.03E+5nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDCN1-like protein 1(Homo sapiens)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM53556(1-(1,3-benzodioxol-5-yl)-3-(1-benzyl-4-piperidyl)u...)
Affinity DataIC50: >6.70E+4nMAssay Description:Binding affinity biotinylated human GST-tagged DCN1 assessed as inhibition of protein interaction with AlexaFluor 488-tagged and N-terminally acetyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed