BDBM54578 1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-propanone::1-[4-(2-fluorophenyl)piperazin-1-yl]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propan-1-one::1-[4-(2-fluorophenyl)piperazino]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propan-1-one::KUC103405N::UNM-0000306122::cid_16002734

SMILES COc1ccc(cc1)-c1noc(CCC(=O)N2CCN(CC2)c2ccccc2F)n1

InChI Key InChIKey=ZICSONYJRWNSDY-UHFFFAOYSA-N

Data  8 KI  8 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 54578   

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  10nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  40nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  60nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  100nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  140nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  170nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataKi:  230nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  748nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  655nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  733nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  632nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  1.11E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  50nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  1.07E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54578(1-[4-(2-fluorophenyl)-1-piperazinyl]-3-[3-(4-metho...)Copy SMILESCopy InChI

Affinity DataEC50:  2.51E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI