BDBM5484 6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine::CHEMBL405259::O6-Substituted Guanine Deriv. 24
SMILES Nc1nc(OCC2=CCCC2)c2[nH]cnc2n1
InChI Key InChIKey=BSCBVJDZICZHJY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 5484
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle
University Of Newcastle
Affinity DataIC50: 1.90E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Zurich
Curated by ChEMBL
University Of Zurich
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University
Curated by ChEMBL
Newcastle University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cellsMore data for this Ligand-Target Pair