BDBM54857 3-[4-[(Z)-3-(4-bromophenyl)-3-keto-prop-1-enyl]-3-(p-tolyl)pyrazol-1-yl]propionic acid::3-[4-[(Z)-3-(4-bromophenyl)-3-oxidanylidene-prop-1-enyl]-3-(4-methylphenyl)pyrazol-1-yl]propanoic acid::3-[4-[(Z)-3-(4-bromophenyl)-3-oxoprop-1-enyl]-3-(4-methylphenyl)-1-pyrazolyl]propanoic acid::3-[4-[(Z)-3-(4-bromophenyl)-3-oxoprop-1-enyl]-3-(4-methylphenyl)pyrazol-1-yl]propanoic acid::BRD-K05011543-001-04-3::cid_5736624

SMILES Cc1ccc(cc1)-c1nn(CCC(O)=O)cc1\C=C/C(=O)c1ccc(Br)cc1

InChI Key InChIKey=ODPJFPAJUAAVPL-FLIBITNWSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 54857   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54857(3-[4-[(Z)-3-(4-bromophenyl)-3-keto-prop-1-enyl]-3-...)
Affinity DataEC50:  3.53E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54857(3-[4-[(Z)-3-(4-bromophenyl)-3-keto-prop-1-enyl]-3-...)
Affinity DataEC50:  2.33E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHuntingtin(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM54857(3-[4-[(Z)-3-(4-bromophenyl)-3-keto-prop-1-enyl]-3-...)
Affinity DataIC50:  2.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54857(3-[4-[(Z)-3-(4-bromophenyl)-3-keto-prop-1-enyl]-3-...)
Affinity DataEC50:  1.93E+4nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM17 leucyl aminopeptidase(Plasmodium falciparum 3D7)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54857(3-[4-[(Z)-3-(4-bromophenyl)-3-keto-prop-1-enyl]-3-...)
Affinity DataIC50:  3.40E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay