BDBM57228 1-allyl-3-[1-(2-pyridyl)ethylideneamino]thiourea::1-prop-2-enyl-3-(1-pyridin-2-ylethylideneamino)thiourea::1-prop-2-enyl-3-[1-(2-pyridinyl)ethylideneamino]thiourea::CHEMBL455284::MLS000564161::SMR000151711::cid_3005984

SMILES CC(=NNC(=S)NCC=C)c1ccccn1

InChI Key InChIKey=FDKSOUXJZSXTHD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 57228   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57228(1-allyl-3-[1-(2-pyridyl)ethylideneamino]thiourea |...)
Affinity DataIC50:  3.27E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM57228(1-allyl-3-[1-(2-pyridyl)ethylideneamino]thiourea |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pHOT DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM57228(1-allyl-3-[1-(2-pyridyl)ethylideneamino]thiourea |...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay