BDBM5837 3-ethyl-1-{4-[(2-{[4-(methanesulfonylmethyl)phenyl]amino}pyrimidin-4-yl)(methyl)amino]phenyl}urea::urea deriv. 28

SMILES CCNC(=O)Nc1ccc(cc1)N(C)c1ccnc(Nc2ccc(CS(C)(=O)=O)cc2)n1

InChI Key InChIKey=KEVIBYPXNNBPSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5837   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5837(3-ethyl-1-{4-[(2-{[4-(methanesulfonylmethyl)phenyl...)
Affinity DataIC50:  26nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed