BDBM65506 CHEBI:80062::Chivosazole F::SCHEMBL1889389

SMILES COC1CC(O)\C=C\C=C\C=C/C(C)C(OC(=O)\C=C/C=C/C=C\C(\C)=C\C(C)C(O)\C=C/C=C/c2coc(n2)C1C)C(C)C(O)CC(C)O

InChI Key InChIKey=ATQKOUYCGKRYRF-GDDXYXLTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 65506   

TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(CHEBI:80062 | Chivosazole F | SCHEMBL1889389)
Affinity DataIC50:  140nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(CHEBI:80062 | Chivosazole F | SCHEMBL1889389)
Affinity DataIC50:  270nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(CHEBI:80062 | Chivosazole F | SCHEMBL1889389)
Affinity DataIC50:  380nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed