BDBM65997 (4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-4-pyrazolyl)methylidene]-1H-pyrazol-5-one::(4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-pyrazol-4-yl)methylidene]-1H-pyrazol-5-one::(4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-ylpyrazol-4-yl)methylidene]-1H-pyrazol-5-one::(4Z)-5-methyl-4-[[1-phenyl-3-(2-thienyl)pyrazol-4-yl]methylene]-2-pyrazolin-3-one::MLS000391933::SMR000260966::cid_6001017

SMILES C=c1[nH][nH]c(=O)c1=Cc1cn(nc1-c1cccs1)-c1ccccc1

InChI Key InChIKey=UGEDTBCQSVJDSD-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 65997   

Target60S ribosomal protein L19-A(Saccharomyces cerevisiae)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM65997((4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-4-pyraz...)
Affinity DataEC50:  3.14E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetVacuolar aminopeptidase 1(Saccharomyces cerevisiae)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM65997((4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-4-pyraz...)
Affinity DataEC50:  1.32E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM65997((4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-4-pyraz...)
Affinity DataIC50:  1.55E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM65997((4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-4-pyraz...)
Affinity DataEC50:  5.14E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM65997((4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-4-pyraz...)
Affinity DataIC50: >4.98E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetBcl-2-like protein 11(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM65997((4Z)-3-methyl-4-[(1-phenyl-3-thiophen-2-yl-4-pyraz...)
Affinity DataEC50:  1.51E+4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay