BDBM6769 3-[1-(3-hydroxypropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::bis-indolylmaleimide deriv. 8d

SMILES OCCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12

InChI Key InChIKey=YNQONPYZDIKVFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6769   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Eli Lilly

LigandPNGBDBM6769(3-[1-(3-hydroxypropyl)-1H-indol-3-yl]-4-(1H-indol-...)
Affinity DataIC50:  1.47E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM6769(3-[1-(3-hydroxypropyl)-1H-indol-3-yl]-4-(1H-indol-...)
Affinity DataIC50:  1.17E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed