BDBM70525 2-mesyl-4-(4-methoxyphenyl)-6-(trifluoromethyl)pyrimidine::4-(4-methoxyphenyl)-2-methylsulfonyl-6-(trifluoromethyl)pyrimidine::MLS000519882::SMR000130297::US11725000, Compound 53::cid_4054690

SMILES COc1ccc(cc1)-c1cc(nc(n1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=PJDOGGJKMHCKOR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 70525   

TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM70525(2-mesyl-4-(4-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataIC50: >4.98E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
National Institute Of Biological Sciences, Beijing

US Patent
LigandPNGBDBM70525(2-mesyl-4-(4-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataEC50: <1.00E+5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM70525(2-mesyl-4-(4-methoxyphenyl)-6-(trifluoromethyl)pyr...)
Affinity DataIC50:  5.47E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay