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BDBM76337 10-methyl-3-(2-pyridin-2-ylethynyl)acridin-9-one::10-methyl-3-[2-(2-pyridinyl)ethynyl]-9-acridinone::10-methyl-3-[2-(2-pyridyl)ethynyl]acridin-9-one::MLS001250121::SMR000685987::cid_24792649

SMILES: Cn1c2ccccc2c(=O)c2ccc(cc12)C#Cc1ccccn1

InChI Key: InChIKey=MRTMIRAOGXBYNB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 76337   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity protein phosphatase (VHR)


(Homo sapiens (Human))
BDBM76337
PNG
(10-methyl-3-(2-pyridin-2-ylethynyl)acridin-9-one |...)
Show SMILES Cn1c2ccccc2c(=O)c2ccc(cc12)C#Cc1ccccn1
Show InChI InChI=1S/C21H14N2O/c1-23-19-8-3-2-7-17(19)21(24)18-12-10-15(14-20(18)23)9-11-16-6-4-5-13-22-16/h2-8,10,12-14H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
PCBioAssay
n/an/a 7.20E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2Z60MHJ
More data for this
Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP)


(Homo sapiens (Human))
BDBM76337
PNG
(10-methyl-3-(2-pyridin-2-ylethynyl)acridin-9-one |...)
Show SMILES Cn1c2ccccc2c(=O)c2ccc(cc12)C#Cc1ccccn1
Show InChI InChI=1S/C21H14N2O/c1-23-19-8-3-2-7-17(19)21(24)18-12-10-15(14-20(18)23)9-11-16-6-4-5-13-22-16/h2-8,10,12-14H,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
PCBioAssay
n/an/a 6.64E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q23R0RBQ
More data for this
Ligand-Target Pair