BDBM77570 3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-prop-2-enyl-1H-1,2,4-triazol-5-one::3-[(5-nitro-2-thiazolyl)thio]-4-prop-2-enyl-1H-1,2,4-triazol-5-one::4-allyl-3-[(5-nitrothiazol-2-yl)thio]-1H-1,2,4-triazol-5-one::4-allyl-5-[(5-nitro-1,3-thiazol-2-yl)thio]-4H-1,2,4-triazol-3-ol::MLS000850992::SMR000457009::cid_2743870

SMILES [O-][N+](=O)c1cnc(Sc2n[nH]c(=O)n2CC=C)s1

InChI Key InChIKey=YSZAZEPYQPEATB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 77570   

TargetRecBCD enzyme subunit RecD(Escherichia coli str. K-12 substr. MG1655)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM77570(3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-prop-2-en...)
Affinity DataIC50:  7.72E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetToll-like receptor 9(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM77570(3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-prop-2-en...)
Affinity DataIC50:  9.60E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM77570(3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-prop-2-en...)
Affinity DataIC50:  1.32E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM77570(3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-prop-2-en...)
Affinity DataIC50:  4.20E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM77570(3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-prop-2-en...)
Affinity DataIC50: >4.98E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay