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BDBM7973 2-aminoethan-1-ol::CHEMBL104943::ethanolamine

SMILES: NCCO

InChI Key: InChIKey=HZAXFHJVJLSVMW-UHFFFAOYSA-N

Data: 3 KI

PDB links: 49 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7973   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Creatine transporter


(Rattus norvegicus)
BDBM7973
PNG
(2-aminoethan-1-ol | CHEMBL104943 | ethanolamine)
Show InChI InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2
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Article
PubMed
9.03E+5n/an/an/an/an/an/an/an/a



Texas Tech University Health Sciences Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male rats


Bioorg Med Chem Lett 14: 3085-92 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.020
BindingDB Entry DOI: 10.7270/Q2BG2PJR
More data for this
Ligand-Target Pair
Glutaminyl Cyclase


(Mus musculus (mouse))
BDBM7973
PNG
(2-aminoethan-1-ol | CHEMBL104943 | ethanolamine)
Show InChI InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2
PDB
MMDB

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1.93E+7 -2.38n/an/an/an/an/a8.030



Probiodrug AG



Assay Description
QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...


Biochemistry 44: 13415-24 (2005)


Article DOI: 10.1021/bi051142e
BindingDB Entry DOI: 10.7270/Q21834QW
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM7973
PNG
(2-aminoethan-1-ol | CHEMBL104943 | ethanolamine)
Show InChI InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2
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Article
PubMed
1.50E+8n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Bioorg Med Chem Lett 20: 4870-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.090
BindingDB Entry DOI: 10.7270/Q29C6XMQ
More data for this
Ligand-Target Pair