BDBM82018 CAS_790::CHEMBL1427::Hypoxanthine::NSC_790

SMILES O=c1[nH]cnc2nc[nH]c12

InChI Key InChIKey=UYLWKSJTHLRFBX-UHFFFAOYSA-N

Data  2 KI  1 Kd  2 ITC

PDB links: 51 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82018   

TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790)
Affinity DataKi:  1.70E+4nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM82018(CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790)
Affinity DataKd:  680nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 82018   

CellPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine

SyringePNGBDBM82018(CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790)
ITC DataΔG°: -7.40kcal/mole logk: 2.70E+5
pH: 7.4 T: 25.00°C 
CellPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine

SyringePNGBDBM82018(CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790)
ITC DataΔH°: -30.6kcal/mole
pH: 7.4 T: 27.00°C