BDBM8443 2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-yl}methylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid::5-[5-(2-Chloro-5-trifluoromethyl-phenyl)-furan-2-ylmethylene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid::BI-11B3::ChemBiolDrugDes71131 Compound 65::Rhodanine analogue

SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)C1=O

InChI Key InChIKey=DCKNCBINJDHCQH-MLPAPPSSSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8443   

TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8443(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataKi:  32nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM8443(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  190nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed