BDBM84866 5'-Deoxy-5'-thiodenosine scaffold, 18
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSCCC(O)CO)[C@@H](O)[C@H]1O
InChI Key InChIKey=QSBLNOGMFRGVGL-HVMNINKTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 84866
TargetPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of Cambridge
University Of Cambridge
Affinity DataKd: 5.40E+5nMpH: 7.6 T: 2°CAssay Description:The dissociation constants and enthalpies was determined by isothermal titration calorimety.Checked by AuthorMore data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 84866
CellPantothenate synthetase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of Cambridge
University Of Cambridge
ITC DataΔH°: -29.9kcal/mole
pH: 7.6 T: 25.00°C
pH: 7.6 T: 25.00°C