BDBM85273 BI-21C5

SMILES Oc1ccccc1-c1cc(-c2ccc3OCOc3c2)c(C#N)c(=O)[nH]1

InChI Key InChIKey=YYGAJCRLZTWLGE-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 85273   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM85273(BI-21C5)
Affinity DataKi:  5.10E+3nMAssay Description:Binding affinity to Bcl-xL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM85273(BI-21C5)
Affinity DataIC50:  5.10E+3nM Kd:  1.98E+4nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed