BDBM85330 CAS_68647::NSC_68647::ONDANSETRON::Ondansetron hydrochloride
SMILES Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C
InChI Key InChIKey=FELGMEQIXOGIFQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 116 hits for monomerid = 85330
Affinity DataKi: 0.770nMAssay Description:Compound was evalated for its in vitro affinity at serotonergic 5-hydroxytryptamine 3 receptor by radioligand binding assay , using [3H]-LY 278584 in...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The binding affinity was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The binding affinity of the compound was measured on imidazoline I2 receptor using [3H]- indazoxan as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor in rat cortical membranes using [3H]5-HT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazineChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor was determined in rat cerebro cortical membranes using [3H]quipazine.More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor of neuronal in the afferent rabbit vagusMore data for this Ligand-Target Pair
Affinity DataKi: 3.31nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heartMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 6.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of binding of [3H]-BRL 43694 to 5-hydroxytryptamine 3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Compound was evaluated for its ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15. More data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 12nMAssay Description:The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 16nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 680nMAssay Description:The binding affinity of the compound was measured on cholecystokinin type B receptor using [3H]- CCK-8 as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 680nMAssay Description:The binding affinity of the compound was measured on sigma receptor using [3H]- (+)-3-PPP as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:In vitro affinity at serotonergic 5-hydroxytryptamine 4 receptor by radioligand binding assay using [3H]GR-113808 in rat striatum membranes.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
National Institute Of Neurological Disorders And Stroke
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of binding of [3H]5-HT to 5-hydroxytryptamine 1 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 4 receptor using [3H]- GR-113,808 as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:The binding affinity of the compound was measured on mu-opiate receptor using [3H]- naloxone as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 1B receptor using [3H]- serotonin as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7(Rattus norvegicus)
Solvay Duphar
Curated by ChEMBL
Solvay Duphar
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
Solvay Duphar
Curated by ChEMBL
Solvay Duphar
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The binding affinity of the compound was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Solvay Duphar
Curated by ChEMBL
Solvay Duphar
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:The binding affinity of the compound was measured on cholecystokinin type A receptor using [3H]- CCK-8 as radioligand.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rattus norvegicus)
Solvay Duphar
Curated by ChEMBL
Solvay Duphar
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine 2 receptor using [3H]- spiperone as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database