BDBM8580 (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}oxane-3,4-diol::Neamine
SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
InChI Key InChIKey=SYJXFKPQNSDJLI-HKEUSBCWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 8580
Affinity DataKi: 4.29E+4nM ΔG°: -5.89kcal/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 4.29E+4nM ΔG°: -5.95kcal/moleT: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of [3H]Rev response element binding to HIV1 biotinylated-Rev protein expressed in Escherichia coli after 15 mins by scintillation proximit...More data for this Ligand-Target Pair
Affinity DataIC50: 3.86E+4nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against peptide binding to the RRE RNA was determinedMore data for this Ligand-Target Pair
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Graduate School Of Bioscience And Biotechnology
Curated by ChEMBL
Graduate School Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Tat peptide binding to HIV-1 TAR RNAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+5nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+5nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.86E+4nMAssay Description:Compound tested in vitro for inhibition of translation using highly active Escherichia coli S30 and a plasmid containing a gene expressing truncated ...More data for this Ligand-Target Pair