BDBM87177 5-fluoranyl-N-[2-[1-(3-fluorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1H-indole-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::5-fluoro-N-[2-[1-(3-fluorophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid::5-fluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-1H-indole-2-carboxamide;2,2,2-trifluoroacetic acid::CHEMBL1254736::VU0366558-1::cid_46938431
SMILES Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2cc3cc(F)ccc3[nH]2)CC1
InChI Key InChIKey=QUYIDBQRQADSRU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 87177
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 25nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 25nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair