BDBM87186 CHEMBL471055::N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenyl-propiolamide;2,2,2-trifluoroacetic acid::N-[2-(4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenyl-prop-2-ynamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenyl-2-propynamide;2,2,2-trifluoroacetic acid::N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenylprop-2-ynamide;2,2,2-trifluoroacetic acid::VU0364187-1::cid_53470118

SMILES O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)C#Cc1ccccc1

InChI Key InChIKey=RPRLOVBRQBKAFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 87186   

TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87186(CHEMBL471055 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)
Affinity DataIC50:  1.64E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87186(CHEMBL471055 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of GFP-labeled PLD2 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM87186(CHEMBL471055 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM87186(CHEMBL471055 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)
Affinity DataIC50:  2.13E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay