BDBM87186 CHEMBL471055::N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenyl-propiolamide;2,2,2-trifluoroacetic acid::N-[2-(4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenyl-prop-2-ynamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenyl-2-propynamide;2,2,2-trifluoroacetic acid::N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-3-phenylprop-2-ynamide;2,2,2-trifluoroacetic acid::VU0364187-1::cid_53470118
SMILES O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)C#Cc1ccccc1
InChI Key InChIKey=RPRLOVBRQBKAFJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 87186
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.64E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of GFP-labeled PLD2 in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.13E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair