BDBM87211 N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-4-chloro-benzamide;2,2,2-trifluoroacetic acid::N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-4-chloranyl-benzamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]propan-2-yl]-4-chlorobenzamide;2,2,2-trifluoroacetic acid::N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-4-chlorobenzamide;2,2,2-trifluoroacetic acid::VU0359591-1::cid_53470188

SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)c1ccc(Cl)cc1

InChI Key InChIKey=BSGGZEUVJPHPOY-AWEZNQCLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 87211   

TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87211(N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)...)
Affinity DataIC50:  890nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87211(N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)...)
Affinity DataIC50:  5nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87211(N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)...)
Affinity DataIC50:  4nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87211(N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)...)
Affinity DataIC50:  400nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay