BDBM87276 MLS000585361::N-(1,3-benzothiazol-2-yl)-9H-xanthene-9-carboxamide::N-1,3-benzothiazol-2-yl-9H-xanthene-9-carboxamide::SMR000204124::cid_2862916

SMILES O=C(Nc1nc2ccccc2s1)C1c2ccccc2Oc2ccccc12

InChI Key InChIKey=NKOPNLUYOHOGFZ-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 87276   

TargetTegument protein VP16(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM87276(MLS000585361 | N-(1,3-benzothiazol-2-yl)-9H-xanthe...)
Affinity DataIC50:  1.25E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear receptor coactivator 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM87276(MLS000585361 | N-(1,3-benzothiazol-2-yl)-9H-xanthe...)
Affinity DataIC50:  1.27E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87276(MLS000585361 | N-(1,3-benzothiazol-2-yl)-9H-xanthe...)
Affinity DataEC50:  4.80E+3nMAssay Description:Positive allosteric modulation of human mGlu1 receptor assessed as increase in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87276(MLS000585361 | N-(1,3-benzothiazol-2-yl)-9H-xanthe...)
Affinity DataEC50:  4.79E+3nMAssay Description:Positive allosteric modulation of human mGlu1 receptor assessed as increase in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor coactivator 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM87276(MLS000585361 | N-(1,3-benzothiazol-2-yl)-9H-xanthe...)
Affinity DataIC50:  7.97E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay