BDBM89825 2-(4-Fluoro-phenyl)-chromen-4-one::2-(4-fluorophenyl)-1-benzopyran-4-one::2-(4-fluorophenyl)chromen-4-one::2-(4-fluorophenyl)chromone::MLS000526645::SMR000117119::cid_261391

SMILES Fc1ccc(cc1)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=ZHXIMGYEMBZGOI-UHFFFAOYSA-N

Data  5 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 89825   

TargetCorticotropin-releasing factor-binding protein(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
Affinity DataEC50: >5.30E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein skinhead-1(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
Affinity DataIC50:  1.92E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
TargetHeat shock protein hsp-16.2(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | 2-(4-fluorophe...)
Affinity DataIC50: >6.40E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay