BDBM92338 Wyq16#

SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)NC(=O)OC(C)C

InChI Key InChIKey=RGTRFWTZGHUUBF-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 92338   

TargetPhosphodiesterase(Trypanosoma cruzi)
University Of North Carolina

LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50:  230nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma cruzi)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50:  230nMAssay Description:Inhibition of N-terminal His6-tagged Trypanosoma cruzi 427 PDEC catalytic domain (270 to 614 residues) expressed in Escherichia coli BL21-CodonPlus c...More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma cruzi)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50:  230nMAssay Description:Inhibition of N-terminal His6-tagged Trypanosoma cruzi 427 PDEC catalytic domain (270 to 614 residues) expressed in Escherichia coli BL21-CodonPlus c...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed